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International Journal of Molecular Biology and Biochemistry

Vol. 5, Issue 2, Part A (2023)

Quantification of PAI biomarker levels in women with polycystic ovary syndrome (PCOS) and healthy controls: An elisa-based analysis

Author(s):

Bisma Ahad and Dr. Kishan Pal

Abstract:

Somewhere in the range of 6 and 10% of ladies of conceptive age experience the ill effects of polycystic ovarian syndrome (PCOS), a common condition. It is described by an abundance of androgen, ovulatory brokenness, and is connected to a few metabolic anomalies, including impeded starch digestion, insulin resistance (IR), weight, and dyslipidemia, which are all unfavorable to ovarian capability and ripeness. Preptin, a peptide chemical delivered pair with insulin by pancreatic cells, is remembered to further develop insulin discharge. Adropin, an as of late found peptide chemical, is fundamental for keeping up with metabolic homeostasis, forestalling insulin resistance, controlling dyslipidemia, and managing unsaturated fat and glucose digestion. Among the earlier causes of metabolic diseases, preptin and adropin appear to be very important. The goals were to pinpoint particular PAI biomarkers that significantly differed between PCOS and controls and to investigate relationships between clinical characteristics and PAI levels. This study highlights the potential clinical value of PAI biomarkers for diagnosis and risk assessment and advances our understanding of PCOS etiology.

Pages: 48-54  |  181 Views  56 Downloads

How to cite this article:
Bisma Ahad and Dr. Kishan Pal. Quantification of PAI biomarker levels in women with polycystic ovary syndrome (PCOS) and healthy controls: An elisa-based analysis. Int. J. Mol. Biol. Biochem. 2023;5(2):48-54. DOI: 10.33545/26646501.2023.v5.i2a.51
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