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International Journal of Molecular Biology and Biochemistry

Vol. 6, Issue 1, Part A (2024)

Correlation between human parvovirus and anemia in pregnant women in Najaf governorate

Author(s):

Faten Abed AL-Kadhem Khalaf Aldawmy, Ahmed S Abed and Saif Jabbar Yasir

Abstract:

Introduction: Due to the parvovirus B19's hazardous effects on expectant mothers and the developing fetus, it warrants special care. It may invade the bone marrow and infect RBC progenitors, and it can undergo latent infection and reactivation.
Objective: The purpose of this study was to ascertain the severity of parvovirus infection in the anemia of pregnant women. 
Methods: In the case-control study, parvovirus was detected in blood serum samples using the ELISA technique, and positive samples were tested using the nested PCR technique. A total of 252 samples were tested by ELISA, and 63.4 % of the samples for anti-Human IgM antibodies against parvovirus. Where 71.4% were positive for anti-HPV B19 IgG antibodies. In a sample of anemic pregnant women, both groups' sample diagnostic utilizing PCR technique for Parvovirus B19 DNA findings revealed that 61.1% had positive DNA. 
Results: A total of 126 control groups of only 6.3% provide a positive result for parvovirus DNA. In subgroup sample diagnosis by PCR technique for the detection of viral DNA, there are also 40.1 % of the first subgroup's PCR approach yielded a mildly positive result, while in moderate anemia it is 50.6 %. The other group (severe anemia) showed that 76.9 % had a positive viral infection.
Conclusion: The relationship is directly proportional between infection with the virus and the increase in anemia in pregnant women suffering from anemia. They showed more viral infections than pregnant women, who did not suffer from anemia. Furthermore, as anemia severity increased, so did virus infection rates.
 

Pages: 07-12  |  165 Views  55 Downloads

How to cite this article:
Faten Abed AL-Kadhem Khalaf Aldawmy, Ahmed S Abed and Saif Jabbar Yasir. Correlation between human parvovirus and anemia in pregnant women in Najaf governorate. Int. J. Mol. Biol. Biochem. 2024;6(1):07-12. DOI: 10.33545/26646501.2024.v6.i1a.57
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